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The Arcuate Nucleus in Control of Food Intake

生理与病理生理学系及糖尿病中心学术活动

题目:The Arcuate Nucleus in Control of Food Intake

讲演人:Michael William Mulholland

                           M.D., Ph.D, Professor and Chair

                           Department of Surgery

                           University of Michigan Medical Center

时间:2008-7-1(Tuesday), 11:30am

地点:生理楼三层会议室

 

Curriculum Vitae - Michael William Mulholland, MD, PhD EDUCATION           1971-Graduation               Stephen Decatur High School, Decatur, Illinois           1971 - 1974       Northwestern University, Evanston, Illinois; B.A.           1974 - 1978      Northwestern University, Evanston, Illinois; M.D.           1978 - 1985      University of Minnesota, Minneapolis, Minnesota; Ph.D. POSTDOCTORAL TRAINING           1978 - 1979        Intern in Surgery, University of Minnesota, Minneapolis, Minnesota           1979 - 1985        Resident in Surgery, University of Minnesota, Minneapolis, Minnesota ACADEMIC, ADMINISTRATIVE, AND CLINICAL APPOINTMENTS        1985- 1988                 Assistant Professor, Department of Surgery, University of Washington        1988- 1991                Assistant Professor, Department of Surgery, University of Michigan              1991- 1995                Associate Professor, Department of Surgery, University of Michigan              1993-  1997  Associate Chairman for Research, Department of Surgery, University of Michigan        1995                          Professor, Department of Surgery, University of Michigan        1997-2002                 Section Head, General Surgery, University of Michigan        1997- 2002               Program Director, General Surgery Residency, University of Michigan        1997- 2000 Associate Chairman for Education, Department of Surgery, University of Michigan        2002- Present    Frederick A. Coller Professor of Surgery and Chairman,                                                   Department of Surgery, University of Michigan        2003- Present               Surgeon in Chief, University Hospital   RESEARCH INTERESTS Dr. Mulholland’s research interests include neurocrine control of pancreatic exocrine secretion and enteric neurobiology. He is the principal director of a research laboratory that has been continuously funded by the NIH since 1988.  In 2004, he received the MERIT Award for his project, Neuropeptide regulation of enteropancreatic function.  The project has been funded through December 2014.    Selected publications (more than140 papers) Lin T, Weizhen Z, Yuexian Hu, Fan Y, Zhao L, Mulholland M: Interluekin-1b and interluekin-6 stimulate matrix metalloproteinase-9 secretion in cultured myenteric glia.  J Surg Res 137:38-45, 2007. Biaoxin C, Li J, Zhang W, Ammori JB, Mulholland MW: Melanocortin-3 receptor activates MAP kinase via P13 kinase. Reg Peptides 139:115-121, 2007. Li, J, Chai, B, Zhang W, Liu Y, Ammori JB, Mulholland MW: Akyrin repeat and SOCS box containing protein 4 (Asb-4) interacts with GPS1 (CSN1) and inhibits c-Jun NH2-terminal kinase activity. Cellular Signalling 19:1185-1192, 2007. Zhang W, Zhao L, Mulholland MW: Ghrelin stimulates myocyte development. Cellular Phys & Biochemistry 20:659-664, 2007. Ammori JB, Zhang W, Newman EA, Mulholland MW: Glutamate-induced calcium transients in neurons of the dorsal motor nucleus of the vagus. J Gastro Surg 11(8):1016-1024, 2007.

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