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T-type Ca2+ Channels and Glucose Desensitization in Beta Cells

生理与病生理学系及糖尿病中心学术活动

题目: T-type Ca2+ Channels and Glucose Desensitization in Beta Cells

主讲人:   Ming Li,Associate Professor

                  Department of Physiology,

                  Tulane University Health Sciences Center, New Orleans, LA

时间:2007-6-13,Wednesday,11:30am

地点:生理楼三层会议室

 

Selected publication:

1.        M. Li, J.D. McCann, C.M. Liedtke, A.C. Nairn, P. Greengard and M.J. Welsh: cAMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium. Nature 331:358-360, 1988.

2.        M. Li, J.D. McCann, M.P. Anderson, J.P. Clancy, C.M. Liedtke, A.C. Nairn, P. Greengard, and M.J.Welsh:  Protein kinase C regulation of chloride channels in normal and cystic fibrosis airway epithelia. Science 244:1353-1356, 1989.

3.        M. Li, J. West, Y. Lai, T. Scheuer, W.A. Catterall: Functional Modulation of Brain Sodium channels by cAMP-dependent Phosphorylation. Neuron 8:1151-1159,1992.

4.        M. Li, J. W. West, R. Numann, B.J. Murphy, T. Scheuer, W.A. Catterall: Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase. Science 261:1439-1442, 1993

5.        L. Huang, A. Bhattacharjee, J. T. Taylor, B. M. Keyser, M. Zhang, L. Marrero, M. Li: [Ca2+]i regulated CaV1.3 translocation in insulin secreting cells. Am J Physiol: Cell Physiol 286: C213–C221, 2004.

6.        J. T. Taylor, L. Huang, B. M. Keyser, H. Zhuang, C. W. Clarkson, M. Li. Role of high-voltage-activated calcium channels in glucose regulated ??cell calcium homeostasis and insulin release. Am J Physiol 289:900-908, 2005

7.        J. T. Taylor, L. Huang, X. Zeng, B. M. Keyser, K. C. Agrawal, J. B. Hansen, M. Li: Selective blockade of T-type Ca2+ channels suppresses human breast cancer cell proliferation. Breast Cancer Res. In Print.

 

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