Organizers

Professional Committee of Microcirculation Chinese Association of Integrative Medicine

President

Jing-Yan Han, M.D, Ph.D.

President, Professional Committee of Microcirculation Chinese Association of Integrative Medicine (PCMCAIM).

Professor and Chair, Department of Integrated Traditional Chinese and Western Medicine, Peking University Health Science Center .

38 Xueyuan Road, Beijing 100191, People’s Republic of China

Tel: 86-10-8280-2862

Fax: 86-10-8280-2996

E-mail: hanjingyan@bjmu.edu.cn

Program

Plenary Lecture:

Walter Duran, Professor and Vice Chair of Physiology and Surgery, New Jersey Medical School Rutgers University .

Geert Schmid-Schoenbein, Professor of Bioengineering, University of California, San Diego .

Sarah Yuan, Professor and Chair, Department of Molecular Pharmacology & Physiology, University of South Florida Morsani College of Medicine.

Makoto Suematsu, Professor and Dean, School of Medicine, Keio

University.

Masato Yasui, Professor and Chair, Department of Pharmacology, School

of Medicine, Keio University .

Pierre Maechler, Professor, Department of Cell Physiology and

Metabolism, University Medical Center , University of

Geneva .

Jing-Yan Han, Professor and Chair, Department of Integrated Traditional Chinese and Western Medicine, Peking University Health Science Center .

Symposium 1  Permeability

Chair:  Jerry Breslin ( University of South Florida )

Masato Yasui ( School of Medicine, Keio University )

Symposium 2  Energy and microcirculation

Chair:  Pierre Maechler ( University of Geneva )

       Fu-Long Liao ( China Academy of Traditional Chinese Medicine)

Symposium 3  Organ injury and microcirculation

     Chair:  Mack Wu ( University of South Florida )

            Qiao-Bin Huang (Southern Medical University )

Symposium 4  Oxidative stress and microcirculation

     Chair:  Makoto Suematsu, ( School of Medicine , Keio

University)

Ke-Sheng Dai ( Soochow University )

Symposium 5  Inflammation and microcirculation

Chair:  Sarah Yuan ( University of South Florida )

Chang-Man Zhou (Peking University Health Science Center)

Symposium 6  Lymphatics

       Chair:  David Zawieja ( Texas A&M University System Health Science Center )

            Xue-Jun Li ( Peking University Health Science Center )

Posters  P-1 Hypertension and microcirculation,

P-2 Hyperlipemia and microcirculation

P-3 Hyperglycemia and microcirculation

P-4 Homocysteine and microcirculation

P-5 Rerperfusion injury and microcirculation

P-6 Shock

P-7 Myocardial damage and microcirculation

P-8 Brain injury and microcirculation,

P-9 Hepatic injury and l microcirculation

P-10 Gastrointestinal injury and microcirculation

P-11 Pulmonary injury and microcirculation

P-12 Eyeground and microcirculation

P-13 Tumor and microcirculation,

P-14 Stress and microcirculation

P-15 Hemorrhage

P-16 Endothelial cell

P-17 Leucocyte

P-18 Platelets

P-19 Mast cell

P-20 Pericytes

P-21 lymph

P-22 Pharmacology of Chinese medicine for microcirculatory

disturbance,

Conference language

English

Registration and Abstract Deadline

For all participants, please submit your English abstract including the title, author, affiliation, purpose, methods, results and conclusion (in one A4 page) before the July 30, 2013. Please also transfer your registration form as well as your abstract by E-mail (weixunhuan@bjmu.edu.cn) to the secretary.

Conference fee

Domestic participants, 1200￥RMB or 200$ USD (Member of PCMCAIM:1000￥RMB).

l       The above fee includes reception party on 6th of September, lunch and dinner on 7th, lunch on 8th of September.

l       Account: please indicate the exact title of unit in postscript of bank transfer draft for which we will write it on invoice. Please also provide us with bank transfer certificate to conference secretariat.

l       We will not responsible for the accommodation and transportation fee.

l       For student registration, 50% discount by providing their students 'id.

Conferencing registration contact:

Na Li

Secretary and assistant, Tasly Microcirculation Research Center, Peking University Health Science Center/Department of Integrated Traditional Chinese and Western Medicine, Peking University Health Science Center

No. 38, Xue Yuan Road , Hai Dian District, Beijing, 100191, China .

E-mail: weixunhuan@bjmu.edu.cn

Telephone：010-8280-2862

Fax No: 010-8280-2996    

  Thesis Abstracts Reference

Treatment of Cardiotonic Pills? after Ischemia-Reperfusion Ameliorates Myocardial Fibrosis in Rats

Xiao-Hong Wei1,3), Yu-Ying Liu1,3), Quan Li1,3), Li Yan1,3), Bai-He Hu1,3), Chun-Shui Pan1,3), Zhi-Xin Li 1,3), Xin Chang1,3); Jing-Yu Fan1,3), Na Zhao1,3), Kai Sun1,3), Ping Huang1,3), Chuan-She Wang1,3), Tai-Ping Fan5), and Jing-Yan Han1,2,3,4)*

1) Tasly Microcirculation Research Cent er, Peking University Health Science Center, Beijing, China

2) Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China

3) Key Laboratory of Microcirculation, State Administration of Traditional Chinese

Medicine of the People's Republic of China

4) Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education of

The People's Republic of China

5) Department of Pharmacology, Trinity College, University of Cambridge, UK

Objective: The present study was designed to evaluate whether CP was beneficial for alleviating myocardial fibrosis following I/R injury.

Methods: Sprague-Dawley rats were subjected to 30 min occlusion of the left anterior descending coronary artery, followed by reperfusion. CP (0.4 or 0.8 g /kg) was daily administrated starting from 3 h after reperfusion until day 6. Coronary venular diameter, RBC velocity, albumin leakage, MBF, heart function, myocardial infarction and fibrosis size, myocardium ultrastructure, MPO activity and MDA level were evaluated. The expression of MCP-1, RP S19, TGF-β1, P-Smad3, Smad4, MMP-9 and α-SMA, and the infiltration of leukocytes were examined.

Results: CP post-treatment ameliorated I/R-induced myocardial RBC velocity reduction, MBF decrease, cardiac dysfunction, and albumin leakage increase. Moreover, myocardial infarction and fibrosis size, MPO activity, MDA level, the expression of RP S19, TGF-β1, P-Smad3, Smad4, MMP-9 and α-SMA, the number of CD68-positive cells increased significantly after I/R, and myocardium collagen deposition was observed on day 6 after reperfusion. All the alterations after I/R were significantly ameliorated by CP.

Conclusions: Post-treatment with CP ameliorates I/R induced myocardial fibrosis, suggesting that CP may be applied as an option for preventing cardiac remodeling after I/R injury.   

International conference for Microcirculation ( Beijing , 2013)

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