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The role of pendrin in blood pressure regulation

生理与病理生理学系及糖尿病中心学术活动

题目:The role of pendrin in blood pressure regulation

讲演人:Susan M. Wall, M.D.

                                     Professor of Medicine and Physiology

                                     Emory University School of Medicine

时间:2008-10-6(Monday),10:30am

地点:生理楼三层会议室

 

Education

Undergraduate Education

       The University of Washington, Seattle, Washington

       B.S. in Chemistry with Honors, cum laude, June 1976

Graduate Education

       St. Louis University, St. Louis, Missouri

       M.D., May 1980

Postgraduate Education

1980-1983                        Internship and Residency, Internal Medicine, UCLA San Fernando Valley Program, Sepulveda, California

1980-1984                        Fellow in Nephrology, U.C.L.A. Center for the Health Sciences and Wadsworth VA Hospital, Los Angeles, California

1980-1985                        Senior Staff Fellow, Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland

1980-1986                        2000-2001        Certificate in Business Administration, Executive Healthcare Training Institute

Academic Appointments

1980-1987                        Assistant Professor of Medicine, The University of Texas Medical School at Houston,   Houston, Texas

1980-1988                        1997-2002  Associate Professor of Medicine (tenure awarded 1998), The University of Texas Medical School at Houston, Houston, Texas

1980-1989                        Regular Faculty, Graduate School of Biomedical Sciences, The University of Texas Medical School at Houston, Houston, Texas

1980-1990                        2003-present     Professor of Medicine with tenure, Emory University School of Medicine

Selected publication

1.                   Pech, V., W. Zheng, T.D. Pham, J.W. Verlander, and S.M. Wall. Angiotensin II activates H+-ATPase in type A intercalated cells in mouse cortical collecting duct. J. Am. Soc. Nephrol. 19: 84-91, 2008.

2.                   Pech, V., Y. H. Kim, A. M. Weinstein, L.A. Everett, T. D. Pham, and S. M. Wall. Angiotensin II increases chloride absorption in the cortical collecting duct in mice through a pendrin-dependent mechanism Am. J. Physiol. 292: F914-F920, 2007.

3.                   Verlander, J.W., Y. H. Kim, W.K. Shin, T. D. Pham, K. A. Hassell, W.H. Beierwaltes, E. D. Green, L.A. Everett, S. W. Matthews  and S. M. Wall. Dietary Cl- restriction upregulates pendrin expression within the apical plasma membrane of type B intercalated cells Am. J. Physiol. 291:  F833-F839, 2006.

4.                   Kim, Y.H., J.W. Verlander, S.W. Matthews, I. Kurtz, I.D. Weiner, W.K. Shin, L.A. Everett, E.D. Green, S. Nielsen, and S.M. Wall.  Intercalated cell H+/ OH- transporter expression is reduced in Slc 26a 4 null mice.  Am. J. Physiol. 289: F1262-F1272, 2005.

5.                   Wall, S.M., Y.-H. Kim, L. Stanley, D.M. Glapion, L.A. Everett, E.D. Green and J.W. Verlander.  NaCl restriction upregulates renal Slc 26a 4 through subcellular redistribution:  role in Cl- conservation.  Hypertension 44:982-987, 2004.

 

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