October 28

Room 414   Yifu Building

13:00-15:00

Symposium 1    Brain Microcirculation and Cerebral Vascular Disease

Chair: Xue-Long Jin / Huai-Lian Guo

13:00-13:25

Paul Fraser: The Role of Free Radical Generation in Increasing Cerebrovascular Permeability

13:25-13:50

Xue-Long Jin: A New Internal Capsule Hemorrhage Animal Model

13:50-14:15

Sheepsumon Viboolvorakul: Exercise Training Ameliorates Age-induced Cerebral Microvascular Deterioration and VEGF Angiogenic Signaling in Rats

14:15-14:30

Lei-Lei Mao: Adoptive Regulatory T Cell Therapy Protects Against Stroke-induced Cerebral Injury

14:30-14:45

Yong-Bo Zhang: The Effects of Rho Kinase Inhibition on the Permeability of Blood-brain Barrier and Activation of Microglia After Cerebral Ischemia in Rats

14:45-15:00

Jiang-Man Song: In vivo Observation of Cortical Astrocytes after Cerebral Hypoperfusion in Mice

15:10-15:40

Plenary Lecture 1    Chair: Geraldine Clough

Professor Hidekazu Suzuki: Organ Microcirculation and Gastrointestinal (GI) Disorders

15:40-16:10

Plenary Lecture 3    Chair: Akos Koller

Professor An Huang: Sexually Dimorphic Regulation of Cardiovascular Function: Roles of EETs/she

16:10-16:40

Plenary Lecture 5    Chair: Suthiluk Patumraj

Professor De-An Guo: Current Status and Future Perspectives in Modernization of Chinese Herbal Medicines

16:40-17:10

Plenary Lecture 7    Chair: Gerald A. Meininger

Professor Nicola J. Brown: Role of the bone microvascular niche in the progression and treatment of tumour metastasis

Room 402   Yifu Building

13:00-15:00

Symposium 2    Cardiovascular Disease and Coronary Microcirculation

Chairs: Ming Xu /Yu-Zhen Li

13:00-13:20

Zi-Jian Li: HIP-55, A Novel Component of Pro-survival Signaling, and Cardiovascular Diseases

13:20-13:40

Ming Xu: The Formation and Stabilization of G-quadruplex by Natural Small Molecule Down-Regulates miR-24 Expression

13:40-14:00

Xiao-Hong Wei: Cardiotonic Pills Ameliorates Ischemia-reperfusion Induced Cardiac Injury in Rats, Relying on the Antioxidant Effect of 3, 4-dihydroxyl-phenyl Lactic Acid and Energy Regulation of Notoginsenoside R1

14:00-14:20

Bao-Hong Jiang: Cardiovascular Protection of Salviae Miltiorrhizae and the Underlying Mechanism

14:20-14:40

Wan-Li Shen: Effects and Mechanisms of Tanshinone IIA Derivative on Ameliorating Myocardial Ischemia/Reperfusion Injury in Rats

14:40-15:00

Jia-Hua Guo: The Modulation of Dantonic？ on the Perturbed Energy Metabolism of the Acute Myocardial Ischemia Model Rats

15:10-15:40

Plenary Lecture 2    Chair: You-Yi Zhang

Professor Xue-Jun Li: Aquaporin-1 Translocation and Degradation Partially Mediates the Water Transportation Mechanism of Acetazolamide

15:40-16:10

Plenary Lecture 4    Chair: Bao-Xue Yang

Assistant Professor Jerome W. Breslin: New Advances to Stop Microvascular Leakage During Inflammation

16:10- 16:40

Plenary Lecture 6    Chair: Tailoi Chan-Ling

Professor Roland N. Pittman: Regulation of Microvascular Blood Flow and Oxygen Supply

16:40- 17:10

Plenary Lecture 8    Chair: Nai-Feng Liu

Professor Ke-Sheng Dai: Receptor-interacting protein kinase 3 promotes platelet activation and thrombosis

October 29

Room 414    Yifu Building

08:00-10:00

Symposium 3    Shock

Chairs: Yong Jiang / Paul Fraser

08:00-08:20

Hui Jin: Microcirculatory Disorders and Protective Role of Anti-oxidant in Severe Heat Stroke: A Rat Study

08:20-08:40

Li-Na Jiang: Effect of Post-hemorrhagic Shock Mesenteric Lymph on Murine CD4+ T cells

08:40-09:00

Kai Sun: Yiqifumai Injection, A Traditional Chinese Compound Medicine, and Its Active Ingredient Ginsenoside Rb1 Ameliorate Microvascular Hyperpermeability Induced by Lipopolysaccharide

09:00-09:20

Peng-Yun Li: Sirtuin 1/3 Prevents Low Vasoreactivity by Modulating Mitochondrial Function

09:20-09:40

Yun-Pei Zhang: Catalpol Restores LPS-elicited Rat Microcirculation Disorder by Regulation of a Network of Signaling Involving Inhibition of TLR-4 and Src

09:40-10:00

Abbas Muhammad: Hypoxia Induces Micro-lymphatic Endothelial Barrier Dysfunction Via Activation of ASK1/p38 MAPK Pathway

10:10-10:40

Plenary Lecture 9    Chair: Fu-Long Liao

Professor Suthiluk Patumraj: Acanthus ebracteatus Vahl suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in cervical cancer implanted nude mice

10:40-11:10

Plenary Lecture 11    Chair: Jerome W. Breslin

Professor Qiao-Bing Huang:Effects of Moesin Phosphorylation in Endothelial Dysfunction Induced by Advanced Glycation Endproducts

11:10-11:40

Plenary Lecture 13    Chair: Toshio Nakaki

Professor Giovanni E. Mann: Metabolic programming of human fetal endothelial and smooth muscle cells in gestational diabetes

11:40-12:10

Plenary Lecture 15    Chair: Giovanni E. Mann

President Makoto Suematsu:CO-Responsive Heme Proteins Regulate Microcirculation and Cancer Proliferation

14:00-16:00

Symposium 5   Diabetes and Microcirculation

Chairs: Qiao-Bing Huang / Akos Koller

14:00-14:25

Fan-Yin Meng: Characterization of Angiogenesis and Endothelial Dysfunction in microRNA-34a Knockout Mice with Diabetic Liver Injury

14:25-14:50

Amporn Jariyapongskul: Effects of Alpha Mangostin on Blood Brain Barrier Permeability in Type 2 Diabetic Rats

14:50-15:15

Bing-Chen Liu: High Glucose Induces Podocyte Foot Process Effacement by Stimulating TRPC6

15:15-15:40

Lin Yao: Obesity-induced Vascular Inflammation and Dysfunction Involves Elevated Arginase Activity

15:40-16:00

Ping Gu: Adipocyte SIRT1 Deletion Impaired Endothelial Function Via Reducing Brown Fat Phenotype in Perivascular Adipose Tissue

16:20-16:50

Plenary Lecture 17    Chair: Hiroshi Nagata

ProfessorJing-Yan Han: The mechanism for Chinese medicine to improve microvescular barrier and intestinal mucosa epithelial barrier.

16:50-17:20

Plenary Lecture 19    Chair: Jing-Yan Han

Professor  Gerald A. Meininger:Remodeling of the Cytoskeleton and Adhesion are Fundamental Processes Coupled to Vascular Smooth Muscle Contraction and Relaxation

Room 402   Yifu Building

08:00-10:00

Symposium 4    Hemorrhage-Thrombus

Chairs: Ke-Sheng Dai / Jian-Bo Wu

08:00-08:20

Jin-Cai Luo: New Regulators of Endothelial Exocytosis and Their Roles in Vascular Hemostasis and Thrombosis

08:20-08:40

Li-Qun Wang: Glycation of Vitronectin Inhibits VEGF-induced Angiogenesis by Uncoupling VEGF Receptor-2-αvβ3 Integrin Cross-talk

08:40-09:00

Rong Yan: Glycoprotein Ibα Clustering Induces Macrophage-mediated Platelet Clearance in the Liver

09:00-09:20

Guo-Qing Zheng: Promoting Blood Circulation for Removing Blood Stasis Therapy for Acute Intracerebral Hemorrhage: A Systematic Review and Meta-analysis

09:20-09:40

Dong Zhao: The Effect of Connexin, Arteriole Membrane Potential and Endoplasmic Reticulum Stress-Induced Apoptosis Pathway on Delayed Cerebral Ischemia after Subarachnoid Hemorrhage

09:40-10:00

Qi Fang: Research Progress on Cerebral Microcirculation

10:10-10:40

Plenary Lecture 10    Chair: Nicola J. Brown

Professor Yong Jiang: Future challenges for sepsis: novel strategies based on big data produced by Omics

10:40-11:10

Plenary Lecture 12    Chair: Makoto Suematsu

Professor Geraldine Frances Clough: Skin microvascular blood flow and oxygenation-adaptive outcomes in obesity and type 2 diabetes mellitus/insulin resistance

11:10-11:40

Plenary Lecture 14    Chair: Gianfranco D Alpini

Professor Si-Feng Chen: Exosomes and Cardiovascular Diseases

11:40-12:10

Plenary Lecture 16    Chair: Qiao-Bing Huang

Professor Gianfranco D Alpini: Vascular factors, angiogenesis and liver diseases

14:00-16:00

Symposium 6   Qi-Blood

Chairs: Shi-Jun Wang / Hao Xu

14:00-14:25

Yuan-Yuan Chen: QiShenYiQi Pills, a Compound in Chinese Medicine, Protects Against Pressure Overload-induced Cardiac Hypertrophy Through a Multicomponent and Multi-target mode

14:25-14:50

Shan Wang: The Proteomic Profiling of Calenduloside E Targets in HUVEC: Design, Synthesis and Application of Biotinylated Probe BCEA

14:50-15:15

Min Wang: Elatoside C Protects the Heart From Ischaemia/Reperfusion Injury Through the Modulation of Oxidative Stress and Intracellular Ca2+ Homeostasis

15:15-15:35

Yuan-Chen Cui: Ginsenoside Rb1 Protects Against Ischemia/Reperfusion-induced Myocardial Injury Via Energy Metabolism Regulation Mediated by RhoA Signaling Pathway

15:35-16:00

Qian Hua: Angiogenesis Promoted by PNS Leading to a Neuroprotective Effects in AD-like Animal Models in a Modern Formula of Traditional Chinese Medicine Tong Luo Jiu Nao

16:20-16:50

Plenary Lecture 18    Chair: Roland N. Pittman

Professor Akos Koller: Failure of the autoregulation of cerebral blood flow by hemodynamic forces

16:50-17:20

Plenary Lecture 20    Chair: Yong Jiang

Professor Tailoi Chan-Ling: The microvascular interface in the Central Nervous System: Normal function and relevance to pathology

Room 408    Yifu Building

08:00-10:00

Free Oral Presentation 1

Chairs: Bao-Liang Sun / Yue-Hong Zheng

08:00-08:12

Xiang-Yu Zhou: Screening and Functional Study of miRNAs in Arteriosclerosis Obliterans

08:12-08:24

Xiao-Hua Guo: The Involvement of Beta-catenin in AGE-induced Endothelial Hyperpermeability

08:24-08:36

Lu Tie: Effects of FOXO1 Mediated Regulation of Mitochondrial Function in Diabetic Wound Healing

08:36-08:48

Wen Yu: Sulfur Dioxide Protects Against Pulmonary Artery Collagen Accumulation in Association With Downregulating TGF-β/Smad Pathway in Pulmonary Hypertensive Rats

08:48-09:00

Ding Zhao: The Amelioration Effects of Berberine on Mesareic Vascular Damage in STZ - induced Diabetic Rats

09:00-09:12

Shuang-Shuang Zhang: GLP-1 Inhibits the Receptor for Advanced Glycation Endproducts to Prevent Podocyte Apoptosis Induced by Advanced Oxidative Protein Products

09:12-09:24

Wei-Ling Wang: Aquaporin-3 Deficiency Slows Renal Cystogenesis via Regulation of AMPK/ERK/mTOR Signaling

09:24-09:36

Supakanda Sukpat: Effect of Low-dose Simvastatin on Therapeutic Efficacy of Mesenchymal Stem Cells (MSCs) Transplantation in Diabetic Wound Healing

09:36-09:48

Zong-Yong Zhang: Enhanced Therapeutic Potential of Nano-curcumin Against Subarachnoid Hemorrhage-induced Blood-brain Barrier Disruption Through Inhibition of Inflammatory Response and Oxidative Stress

09:48-10:00

Li-Min Zhang: Estrogen Treatment Improves Lymphatic Contractility in Rats Following Hemorrhagic Shock

教育讲演

October 29

Room 408    Yifu Building

14:00-14:30

Education lecture 1   

Methods for Study of the Organ Microcirculation

脏器微循环的研究方法

Speaker: Yu-ying Liu

Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China

Chair: Dong Han

Professor, National Center for Nanoscience and Technology

14:30-15:30

Education lecture 2   

Attenuating Effect and Underlying Mechanism of Compound Chinese Medicine on Ischemia and Reperfusion Induced Cerebral and Cardiac Microcirculation Disturbance and Organ Injury

心脑微循环障碍与中医药

Speaker: Jing-Yan Han

Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University

Chair: Yi-Ning Huang

Professor and Chairman, Department of Neurology, Peking University First Hospital

15:30-16:00

Education lecture 3   

An update of the journal Microcirculation

Speaker: Geraldine Frances Clough

Deputy Editor-in-Chief, Microcirculation

Professor, Vascular Physiology, Faculty of Medicine, University of Southampton, UK

Chair: Jian-Bo Wu

Professor, Drug Discovery Research Center, Southwest Medical University

October 30

Room 408    Yifu Building

08:00-10:00

Symposium 7    Blood stasis and Phlegm-stasis

Chairs: Yan Zhu / Yan Lei

08:00-08:20

Mei Xue: Panax Notoginseng Saponins Superior to Aspirin in Inhibiting Platelet Adhesion to Injured Endothelial Cells Through COX Pathway

08:20-08:40

Jing-Na Deng: Deepure Tea Improves High Fat Diet-induced Insulin Resistance and Non-alcoholic Fatty Liver Disease

08:40-09:00

Yan Zhu: Coordinated Activation of VEGF/VEGFR-2 and PPARD Pathways by a Multi-component Chinese Medicine DHI Accelerated Recovery from Peripheral Arterial Disease in Type 2 Diabetic Mice

09:00-09:20

Chun-Shui Pan: Post-treatment with Ma-Huang-Tang Ameliorates Cold-warm-cycles Induced Rat Lung Injury

09:20-09:40

Wei Li: Protective Effect of Curcumin Against Cerebral Ischemia-reperfusion Injury in Rats

09:40-10:00

Lei Li: Pharmacological Assessment of the Efficacy of Traditional Chinese Medicine for Coronary Heart Disease of Phlegm-stasis Syndrome

10:10-10:40

Plenary Lecture 21   Chair: Hong-Quan Zhang

Professor Hiroshi Nagata: Migration of Lymphoid and Cancer Cell in Gut-Associated Lymphoid Tissue

10:40-11:10

Plenary Lecture 23    Chair: Jian-Bo Wu

Professor Michael A. Hill:Contribution of At1r Mechanoactivation to the Arterial Myogenic Response and its Regulation by Rgs5 Protein in Skeletal Muscle Arterioles

11:10-11:40

Plenary Lecture 25    Chair: Jing-Yan Han

Professor Toshio Nakaki: Micro RNA in regulating oxidative stress in neurons

Room 402   Yifu Building

08:00-10:00

Symposium 8    New Technique

Chairs: Gang-Min Ning / Feng Han

08:00-08:20

Feng Han: Visualization of the Inflammatory Response During Neurovascular Damage: Communication Between Microvessel and Microglia

08:20-08:40

Ruo-Fan Wang: A Mathematical Model for the Interaction of Nitric Oxide and Oxygen in the Microcirculation Network

08:40-09:00

Xia-Bing Huang: Tissue Viability Imaging for Reconstructive Plastic Surgery

09:00-09:20

Jing Li: High-speed Atomic Force Microscopy for Nano-visualization of Living Biological Samples

09:20-09:40

Ming-Ming Gao: Generation of Human-like Small Rodent Models for Dyslipidemic and Atherosclerotic Studies: CRISPR/Cas9 Mediated Gene Targeting of Syrian Golden Hamsters

09:40-10:00

Xiang Li: Deep RNA Sequencing Elucidates MicroRNA Regulated Molecular Pathways in Ischemic Cardiomyopathy (ICM) And Non Ischemic Cardiomyopathy (NICM)

10:10-10:40

Plenary Lecture 22    Chair: Jun-Bao Du

Professor Jian-Bo Wu: Regulation of Plasminogen Activator Inhibitor-1 in vessel maturation

10:40-11:10

Plenary Lecture 24    Chair: Xue-Jun Li

Professor Masato Yasui:Aquaporins in brain disorders

11:10- 11:40

Plenary Lecture 26    Chair: Ke-Sheng Dai

Professor Gang-Min Ning: Modelling the Flow Pulsatility in Microcirculation Network

Room 409    Yifu Building

08:00-10:00

Free Oral Presentation 2 (中文报告)

Chairs: Zi-Gang Zhao / Qing-Fu Zhang

08:00-08:12

Di Nan: In Vivo Morphological Observation of Cortical Vessel in Cerebral Hypoperfusion Mice

08:12-08:24

Yingli Yu: Cardioprotective Effects of Gypenoside XVII on Endoplasmic Reticulum Stress-Mitochondrial Damage Crosstalk after Ischemia-reperfusion Injury through PI3K/AKT and P38 Signalling Pathways

08:24-08:36

Hou-Yuan Hu: Staphylococcal SSL5-induced Platelet Microparticles Provoke Proinflammatory Responses Via the CD40/TRAF6/NFκB Signaling Pathway in Monocytes

08:36-08:48

Yan Pan: Role of Vimentin in the Inhibitory Effects of Low-Molecular-Weight Heparin on PC-3M Cell Adhesion to, and Migration through, Endothelium

08:48-09:00

Lei Lei: MAPK Signaling

09:00-09:12

Yong-Xia Wang: Density and Kinetics of Ito、IK1、IKs and IKr in Guinea Pig ventricular Myocytes：Implications for Arrhythmogenesis in Humans

09:12-09:24

Xue-Hui Zhang: Cardioprotective Effects of Rosa Rugosa Flavoniods on Myocardial Ischemia Reperfusion Injury in Mice

09:24-09:36

Ya-Qian Huang: Endogenous Sulfur Dioxide Alleviates Collagen Remodeling via Inhibiting TGF-β/Smad Pathway in Vascular Smooth Muscle Cells

09:36-09:48

Wen-Long Xue: H2S Regulates Endothelial Nitric Oxide Synthase Protein Stability by PromotingmicroRNA-455-3p Expression

09:48-10:00

Shu-Xian Han: Adhesion Under Different Flow Conditions