崔庆华

 

 

电话：15801250611（手机）

电话: 010-82801001（办公室）

Email: cuiqinghua@bjmu.edu.cn

 

研究方向

崔庆华目前主要研究方向为医学生物信息学，围绕着(1)心脑血管疾病、癌症、糖尿病等重大复杂疾病关键miRNA/lncRNA的计算机识别、(2)miRNA/lncRNA在疾病中调控规律的数据挖掘、(3)基于RNA的计算机辅助药物研发等科学问题，在Nucleic Acids Research、Bioinformatics等杂志发表第一作者(含共同)SCI论文7篇，通讯作者(含共同)SCI研究论文60篇，创建医学生物信息学平台30余个。他主持和参与了NSFC、科技部等课题10余项。2014年获得国家自然科学基金委优秀青年基金支持。已授权中国专利、国际专利和美国专利各1项。

 

代表性论著：

1. Song F, Cui C, Gao L*, and Cui Q*. miES: predicting the essentiality of miRNAs with machine learning and sequence features. Bioinformatics. 2018 Aug 28.

2. Zhou Y*, Zeng P, Li Y, Zhang Z, Cui Q*. SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features. Nucleic Acids Res 2016 Jun 2;44(10):e91.

3. Wang J, Ma R, Ma W, Chen J, Yang J*, Xi Y*, Cui Q*. LncDisease: a sequence based bioinformatics tool for predicting lncRNA-disease associations. Nucleic Acids Res 2016 May 19;44(9):e90.

4. Li J*, Ma W, Zeng P, Wang J, Geng B, Yang J, and Cui Q*. LncTar: a tool for predicting the RNA targets of long noncoding RNAs. Briefings in Bioinformatics 2015 16(5):806-12.

5. Chen G, Wang Z, Wang D, Qiu C, Liu M, Chen X, Zhang Q, Yan G*, and Cui Q*. LncRNADisease: a database for long noncoding RNA associated diseases. Nucleic Acids Research. 41, 983-986, 2013. (SCI引用357次)

6. Chen G, Wang J*, and Cui Q*. Could circulating microRNAs contribute to cancer therapy. Trends in Molecular Medicine . 2013 19 (2), 71-73.

7. Wang D, Wang, J, Lu M, Song F, and Cui Q*. Inferring the human microRNA functional similarity and functional network based on microRNA-associated diseases. Bioinformatics 2010 26: 1644-1650. (SCI引用170次)

8. Lu M, Zhang Q, Deng M, Miao J, Guo Y, Gao W, Cui Q*. An analysis of human microRNA and disease associations. PLoS ONE. 2008;3(10):e3420. (SCI引用489次)

9. Cui Q, Ma Y, Jaramillo M, Bari H, Awan A, Yang S, Zhang S, Liu L, Lu M, O'Connor-McCourt M, Purisima EO, Wang E. A map of human cancer signaling. Mol Syst Biol 2007 3:152. (SCI引用191次)

10. Cui Q#, Yu Z#, Purisima EO, Wang E. Principles of microRNA regulation of a human cellular signaling network. Mol Syst Biol 2006 2:46. (SCI引用276次)